Leading the Paradigm Shift in Skin Boosters via Supercritical CO₂ Processed Acellular Human Dermal Matrix (E-cell™)

  Dr. Hyo-Hyun Seok, Medical Director of AllLiting Plastic Surgery, has been officially appointed as a Key Opinion Leader (KOL) for 'Juveàcell', a 5th-generation skin booster derived from human dermal components gaining immense traction in the global aesthetic market. This appointment recognizes Dr. Seok’s extensive clinical experience in anti-aging procedures and his contributions to establishing safe, highly effective treatment protocols.

 Juveàcell is an innovative Extracellular Matrix (ECM) booster launched by Vaim Co., Ltd. While conventional skin boosters focus on inducing collagen synthesis indirectly, Juveàcell utilizes proprietary 'Supercritical CO₂ Decellularization Technology (E-cell™ Technology)' to completely eliminate immunogenic substances from human dermal tissue, directly supplying pure human collagen and ECM structural scaffolds into the skin. This minimizes chemical solvent residues and immediately reinforces the structural framework of the skin, demonstrating exceptional efficacy in enhancing elasticity, restoring natural volume, and refining texture.

 As a designated Key Opinion Leader, Dr. Seok will actively engage in academic research, medical seminars, and live surgery demonstrations, providing authoritative clinical guidelines to medical professionals. Juveàcell is supplied in a pre-filled syringe format requiring no reconstitution prior to treatment, significantly reducing the risk of nodule formation or clumping while enabling customized applications for delicate facial zones such as the infraorbital region, cheeks, and perioral lines.

 Dr. Hyo-Hyun Seok stated, "I am honored to serve as a Key Opinion Leader for Juveàcell, an advanced solution that simultaneously addresses skin density improvement and safety—two factors previously lacking in traditional skin boosters. Since every patient exhibits distinct skin thickness and aging velocity, I will continue my academic and clinical endeavors to deliver the safest and most natural skin regeneration outcomes through tailored 3% and 8% concentration protocols."

[Media Q&A] Insights on the 5th-Generation Skin Booster with Juveàcell KOL Dr. Hyo-Hyun Seok of AllLiting Plastic Surgery

Q1. Congratulations on your appointment as a Key Opinion Leader for Juveàcell. Could you share your thoughts?

 "Thank you. It is truly meaningful to serve as a Key Opinion Leader for Juveàcell, which is recognized as one of the most innovative hADM (Human Acellular Dermal Matrix) solutions in the medical aesthetic market. My primary value as a surgeon is delivering 'safe yet definitive outcomes.' Because Juveàcell satisfies both criteria, I look forward to sharing my clinical expertise with colleagues to foster a safer, more effective treatment culture."

Q2. Excellent skin boosters like Rejuran and Juvelook are already established. What is Juveàcell’s biggest differentiator?

 "In short, it is the fundamental difference between a 'signaling stimulant' and 'pre-fabricated construction material.' Traditional products stimulate fibroblasts to encourage collagen synthesis. In contrast, Juveàcell directly implants pure human collagen and ECM—the essential structural foundation of the human dermis. By immediately reinforcing the collapsed skin structure without waiting for self-collagen production, patients with thin, sagging skin experience far more direct and visible regenerative results."

Q3. Juveàcell comes in 3% and 8% concentrations. How do you apply them differently in clinical practice?

 "Applications are strictly customized according to the patient's skin condition and target depth. Juveàcell 3% is ideal for refining skin texture, brightening tone, and tightening thin dermal surfaces, administered densely using manual micro-injections or automated injectors. Juveàcell 8% features a significantly higher collagen concentration and is injected via cannula into deeper layers to increase skin density or add subtle volume to the under-eyes, anterior cheeks, and nasolabial folds, creating a natural, self-regenerated dimensional look rather than an artificial filler appearance."

Q4. Many patients express concern over nodules or severe pain during skin booster treatments. How does Juveàcell perform?
 

 "Its performance is exceptional. Previous powder-form dermal products required reconstitution with saline, risking clumping if insufficiently dissolved. Juveàcell is manufactured as a uniform liquid in pre-filled syringes through advanced processing, dramatically lowering nodule risks. Regarding discomfort, while a slight tightness may occur due to viscosity, the Supercritical CO₂ process minimizes inflammatory responses, resulting in noticeably less pain and higher patient comfort compared to 1st or 2nd generation products."

Q5. What advice would you offer to patients considering Juveàcell treatments?

 "Juveàcell serves as a superior alternative for individuals experiencing thinned skin and sudden loss of elasticity due to aging. However, even premium formulations require precise evaluation of skin thickness and aging progression. I strongly recommend consulting a qualified specialist with extensive anatomical knowledge and clinical expertise to ensure accurate dosage and depth mapping for your specific needs."